DNA tests on samples found in her home and car have drawn a blank.
Cops used revolutionary familial testing to try to identify similar profiles.
North Yorkshire Police were conducting a review into the original probe.
Claudia vanished in 2009, aged 35. She failed to turn up for work as a chef at York University.
Five men later held on suspicion of murder were released without charge.
Det Supt Dai Malyn said: “These inquiries have been worthwhile but have concluded without identifying a suspect.
“This is naturally very frustrating. Our thoughts are with Claudia’s family who remain desperate for a breakthrough.”
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Missing Claudia Lawrence's mum, Joan thinks her daughter is still being held captive by abductor
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